Selasa, 12 Juli 2011
HYPERTHERMIA IN CANCER TREATMENT
Breaf hyperthermia
The healing effect of heat treatment as in the advanced civilizations of ancient Egypt (2400 BC) mentioned, but only doctors of ancient Greece used this therapeutic approach has always recognized and called by heating (Greek:. Hyperthermia) "Give me the power to produce fever and cure of all diseases, "said Parmenides, a Greek physician, 540-480 BC
Hyperthermia in cancer treatment
Hyperthermia (heat therapy or as a thermal therapy) is an acute disease that occurs when the body produces or absorbs more heat than it can be removed. It is usually caused by prolonged exposure to high temperatures. The mechanisms that the body heat eventually overwhelmed and unable to adjust to work effectively with the heat, whereby the body temperature to rise unchecked.
Hyperthermia can be created artificially by drugs or medical devices. In these cases, to cancer and other diseases to treat. Cancer cells are more sensitive to heat than healthy cells and its structure responds differently to overheating. In 1910, the possibility of overheating, the effect of radiation on tumors malware was first described. This method is known and applied rediscovered as a "whole-body hyperthermia" in the early 1960s. Since the 70s a number of studies have been conducted to investigate this form of therapy.
Research has shown that high temperatures (up to 44 ° C) in damage and kill cancer cells, usually with minimal damage to healthy tissue. To kill cancer cells and damaging proteins and structures within cells, hyperthermia may shrink tumors one.
Hyperthermia is almost always used with other forms of treatment for cancer such as radiotherapy and chemotherapy. Hyperthermia may make some cancer cells more sensitive to radiation or other damage to cancer cells, radiation cannot harm. When hyperthermia and radiation therapy are combined, often occurs in one hour intervals. Hyperthermia, the effect of certain anticancer drugs, which reinforce each other and thus more likely to heal - the so-called synergistic effect of hyperthermia. It was found that cytotoxic drugs (chemotherapy agents) more aggressive at temperatures above 40 ° C in the range of normal body temperature
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